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Schwartz, Nancy B.
One or more keywords matched the following properties of Schwartz, Nancy B.
PropertyValue
keywords CNS development
keywords Genetic disorders
overview This program has evolved from the basic biochemistry and enzymology of glycoconjugate structure, function, and synthesis to the study of glycoconjugates in cartilage development, including the identification of gene defects in disorders of skeletal development and chondrodystrophies and the underlying pathophysiology of the matrix deficiencies. A second major area of interest involves CNS development, and the role of gliogenesis and glial cell function in traumatic brain injury, infection and developmental disorders.
One or more keywords matched the following items that are connected to Schwartz, Nancy B.
Item TypeName
Concept Ascorbic Acid Deficiency
Concept Chondrosarcoma
Concept Brain Injuries
Concept Brain
Concept Brain Chemistry
Concept Cartilage Diseases
Concept Growth Disorders
Concept Encephalitis
Concept Dwarfism
Concept Glioma
Concept Osteogenesis Imperfecta
Concept Liver Neoplasms
Concept Inflammation
Concept Carcinoma, Hepatocellular
Concept Mesonephroma
Concept Neuronal Ceroid-Lipofuscinoses
Concept Osteochondrodysplasias
Concept Embryonic and Fetal Development
Concept Poultry Diseases
Concept Tryptophan
Concept Hyperoxia
Concept Limb Deformities, Congenital
Concept Neoplasms, Experimental
Concept Sequence Deletion
Concept Gene Expression Regulation, Developmental
Concept Brain Neoplasms
Concept Disease Models, Animal
Concept Neuroblastoma
Concept Oligodendroglioma
Concept Chromosome Breakage
Academic Article S103L reactive chondroitin sulfate proteoglycan (aggrecan) mRNA expressed in developing chick brain and cartilage is encoded by a single gene.
Academic Article The nanomelic mutation in the aggrecan gene is expressed in chick chondrocytes and neurons.
Academic Article Structural and functional analysis of the chick chondroitin sulfate proteoglycan (aggrecan) promoter and enhancer region.
Academic Article Two immunologically and developmentally distinct chondroitin sulfate proteolglycans in embryonic chick brain.
Academic Article Developmental expression of the HNK-1 carbohydrate epitope on aggrecan during chondrogenesis.
Academic Article Aggrecan regulates telencephalic neuronal aggregation in culture.
Academic Article Aggrecan is expressed by embryonic brain glia and regulates astrocyte development.
Academic Article Proteoglycans in brain development.
Academic Article Sulfation of chondroitin sulfate proteoglycans is necessary for proper Indian hedgehog signaling in the developing growth plate.
Academic Article Large chondroitin sulfate proteoglycans of developing chick CNS are expressed in cerebral hemisphere neuronal cultures.
Academic Article Aggrecan modulation of growth plate morphogenesis.
Academic Article Reconstitution of adenosine 3'-phosphate 5'-phosphosulfate transporter from rat brain.
Academic Article Sulfate-activating enzymes in normal and brachymorphic mice: evidence for a channeling defect.
Academic Article Developmental expression of S103L cross-reacting proteoglycans in embryonic chick.
Academic Article Astrocyte precursor response to embryonic brain injury.
Academic Article Glial migratory streams in the developing hindbrain: a slice culture approach.
Academic Article Defect in proteoglycan synthesis in brachymorphic mice.
Academic Article Brain aggrecan.
Academic Article Chondroitin sulfate proteoglycan expression during neuronal development.
Academic Article Deletion and site-directed mutagenesis of the ATP-binding motif (P-loop) in the bifunctional murine ATP-sulfurylase/adenosine 5'-phosphosulfate kinase enzyme.
Academic Article Increased extracellular magnesium modulates proliferation in fetal neural cells in culture.
Academic Article Neutral sphingomyelinase 2 deficiency increases hyaluronan synthesis by up-regulation of Hyaluronan synthase 2 through decreased ceramide production and activation of Akt.
Academic Article Defect in 3'-phosphoadenosine 5'-phosphosulfate synthesis in brachymorphic mice. II. Tissue distribution of the defect.
Academic Article Kinetic analysis of 'rapid onset' neurite formation in NG108-15 cells reveals a dual role for substratum-bound laminin.
Academic Article Aggrecan is required for growth plate cytoarchitecture and differentiation.
Academic Article 3D high spectral and spatial resolution imaging of ex vivo mouse brain.
Academic Article Delivery and tracking of quantum dot peptide bioconjugates in an intact developing avian brain.
Award or Honor Receipt Research Career Development Award
Academic Article Proteoglycans in brain development and pathogenesis.
Academic Article Glial cell responses in a murine multifactorial perinatal brain injury model.
Academic Article Global Brain Transcriptome Analysis of a Tpp1 Neuronal Ceroid Lipofuscinoses Mouse Model.
Academic Article Brain transcriptome analysis of a CLN2 mouse model as a function of disease progression.
Academic Article Roles of Chondroitin Sulfate Proteoglycans as Regulators of Skeletal Development.
Search Criteria
  • Brain
  • development
  • disorders